Framingham "Teaching" Data

Frmingham "Teaching" Data Set

SAS code to access the data, Proc Print output, Proc Means output.

Brief Description

The Framingham Heart Study is a long term prospective study of the etiology of cardiovascular disease among a population of free living subjects in the community of Framingham, Massachusetts. The Framingham Heart Study was a landmark study in epidemiology in that it was the first prospective study of cardiovascular disease and identified the concept of risk factors and their joint effects. The study began in 1948 and 5,209 subjects were initially enrolled in the study. Participants have been examined biennially since the inception of the study and all subjects are continuously followed through regular surveillance for cardiovascular outcomes. Clinic examination data has included cardiovascular disease risk factors and markers of disease such as blood pressure, blood chemistry, lung function, smoking history, health behaviors, ECG tracings, Echocardiography, and medication use. Through regular surveillance of area hospitals, participant contact, and death certificates, the Framingham Heart Study reviews and adjudicates events for the occurrence of Angina Pectoris, Myocardial Infarction, Heart Failure, and Cerebrovascular disease.

The enclosed dataset is a subset of the data collected as part of the Framingham study and includes laboratory, clinic, questionnaire, and adjudicated event data on 4,439 participants. Participant clinic data was collected during three examination periods, approximately 6 years apart, from roughly 1956 to 1968. Each participant was followed for a total of 24 years for the outcome of the following events: Angina Pectoris, Myocardial Infarction, Atherothrombotic Infarction or Cerebral Hemorrhage (Stroke) or death. The data is provided in Longitudinal form. Each participant has 1 to 3 observations depending on the number of exams the subject attended. Event data for each participant has been added without regard for prevalent disease status or when examination data was collected. For example, consider the following participant:

RANDID age SEX time period prevmi mi_fchd timemifc
95148   52  2     0    1       0       1     3607
95148   58  2  2128    2       0       1     3607
95148   64  2  4192    3       1       1     3607

Participant 95148 entered the study (time=0 or period=1) free of prevalent myocardial damage (prevmi=0 at period=1); however, during followup, an MI event occurred at day 3607 following the baseline examination. The MI occurred after the second exam the subject attended (period=2 or time=2128 days), but before the third attended exam (period=3 or time=4192 days ). Since the event occurred prior to the third exam, the subject was prevalent for MI (prevmi=1) at the third examination. Note that the event data (mi_fchd, timemifc) covers the entire followup period and does not change according to exam.