Department of Statistics Seminar
North Carolina State University

presents

Dr. Zhao-bang Zeng

NC State University

"Gene Expression QTL Analysis: From QTL to Genes to ..."

ABSTRACT

QTL analysis has changed the study of genetic basis of complex traits. With the availability of dense genome-wide molecular markers, it is now possible to map many biologically, medically or agriculturally important QTL into genomic regions for further study. However, there is a major limitation for QTL study. The genomic regions for many mapped QTL are too large for the identification of causal genes. Recently gene expression microarray technology has been used in combination with molecular markers to help for the gene identification and also for elucidating the genetic pathways for complex traits. In this talk, I will outline the statistical problems and discuss challenges for gene expression QTL analysis. I will present the results of our data analysis on two data sets, one on Eucalyptus and another on yeast.

Friday, September, 23, 2005

3:35 - 4:35 pm

206 Cox Hall

Refreshments will be served on the second floor of Dabney Hall (left of Room 222) at 3:00 pm.