Statistical Issues in Mass Spectrometry Based Proteomics

David Muddiman
Department of Chemistry
North Carolina State University

4:00-5:00 pm
Thursday, April 26, 2007
208 Patterson Hall, NCSU Campus
Refreshments at 3:40 pm outside of 208 Patterson

Proteomics is the study of a proteome; a proteome is defined as the proteins expressed by a genome at a specific point in time. Proteins define the function and dysfunction of system - in other words, a phenotype. There are numerous statistical issues in the field of proteomics including efficient experimental design, protein identification, and differential protein expression (e.g., disease versus control). This presentation will cover the basics of mass spectrometry, proteomics, and how statistics is desperately needed.


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